The boys from South Park, Colo., will do their part to spread the word — good, bad and ugly — about getting vaccinated for the COVID-19 pandemic.

The hour-long supersized episode titled South ParQ Vaccination Special  premieres on Wednesday, March 10 at 8 p.m. ET/PT on Comedy Central with two encore airings at 9 p.m. ET/PT and 10 p.m. ET/PT. The premiere will simulcast on MTV2. The new episode follows cable’s #1 scripted telecast of 2020, South ParQ’s The Pandemic Special, which will be rebroadcasted at 7 p.m. ET/PT.