Want to see Bill Hader and Kristen Wiig play twins who haven’t seen nor spoken to each other in 10 years, reunite? That’s the essence of The Skeleton Twins, the new film directed and co-written by Craig Johnson with Mark Heyman.

It co-stars Luke Wilson, Ty Burrell and Boyd Holbrook.

The Skeleton Twins already has won the Waldo Salt Screenwriting Award at the 2014 Sundance Film Festival. Presented by Lionsgate & Roadside Attractions, it’ll open in cinemas on Sept. 19, 2014.

Roll the clip!